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. 2013 Oct 17;5(10):1799–1813. doi: 10.3390/toxins5101799

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© 2013 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Effect of the sponge extracts on coagulation induced by B. jararaca or L. muta. B. jararaca (Panel A) or L. muta (Panel B) venoms were incubated with 0.5% DMSO (column 0), M. angulosa (column 1), C. collectrix (column 2), T. ignis (column 3), A. fulva (column 4), D. etheria (column 5), D. anchorata (column 6), A. viridis (column 7), P. citrina (column 8), P. janeirensis (column 9), H. heliophila (column 10), for 30 min at room temperature. After the mixture was added to the plasma, the clotting time was recorded, as described in the Methods. Data are expressed as means SEM of three individual experiments (n = 3). * Significance level (p < 0.05) when compared to column 0.