Figure 3.

Pancreatic damage during experimental pancreatitis. The time course over 24 hours is shown for (a) serum amylase activity, (b) serum lipase activity, and (c) pancreatic edema. Enzyme activities were measured as indicated in Methods, and the increase in pancreatic water content was determined indirectly as increase in pancreatic weight. Data points represent the means of six or more pancreatitis animals (n ≥ 4 for controls) at each interval ± SEM. ^ASignificant differences (P < 0.05) between the CTSB^+/+ and the CTSB^–/– mice.