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. 2013 Oct 31;3:3105. doi: 10.1038/srep03105

Figure 1. p53312A/A mice are more susceptible to tumour development following exposure to MNU than both wild type and E2F1−/− mice.

Figure 1

Kaplan-Meier survival curves illustrating the time taken to develop tumours following injection with MNU. p53312A/A mice are significantly more liable to develop tumours than both wild type (A) and E2F1−/− (B) mice (p < 0.05). In contrast p53312A/A; E2F1−/− mice are neither significantly more susceptible to tumours than wild type mice (C) nor significantly more resistant than p53312A/A mice (p > 0.05) (D). Loss of E2F1 alone had little effect upon tumour susceptibility compared with both wild type (E) and p53312A/A; E2F1−/− mice (F).