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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Cancer Prev Res (Phila). 2013 Mar 26;6(5):10.1158/1940-6207.CAPR-12-0322. doi: 10.1158/1940-6207.CAPR-12-0322

TABLE 2.

Erlotinib Non-compartmental Pharmacokinetic Parameters in Female Sprague-Dawley Rats and Humans (steady state)

Species Dose
mg/kg
Tmax
h
Cmax
ng/mL
AUC0–24
ng h/mL
T1/2
h
Rat 6 2.00 708 4680 4.61
42 8.00 1590 28400 8.06
Human 150 (mg) 2.44 1740 26500 24.4