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. 2013 Oct 31;3:273. doi: 10.3389/fonc.2013.00273

Table 1.

Myc overexpression in PCa.

Tumor type Method Citation
% 8q GAINa
38 Primary + LN met SNP, qPCR Liu et al. (108)
27 Primary + LN met CGH Lapointe et al. (53)
72 CRPC CGH Nupponen et al. (54)
% 8q24 GAINa
9 Primary (LG) FISH Gurel et al. (50, 55)
28 Primary (HG) FISH Gurel et al. (50, 55)
% Myc GAINa
77 CRPC FISH Nupponen et al. (54)
21 Primary DNA array Edwards et al. (56)
63 CRPC DNA array Edwards et al. (56)
Myc IHC SCORE
2.6 Normal IHC Gurel et al. (50, 55)
8.6 LG-PIN IHC Gurel et al. (50, 55)
25.8 HG-PIN IHC Gurel et al. (50, 55)
27.1 Primary IHC Gurel et al. (50, 55)
14.9 Met IHC Gurel et al. (50, 55)

a Percentage of tumors displaying the change.

LN, lymph node; CRPC, castration-resistant PCa; LG, low grade; HG, high grade; Met, metastasis.