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. 2013 Feb 15;32(17):2893–2901. doi: 10.1002/sim.5757

Table II.

Bias of the naive estimator and probabilities of various outcomes when two experimental treatments are tested in stage 2 for the case where θ1 = θ2 = 0.05 and the case where θ1 = 0.025 and θ2 = 0.05.

Characteristic t = 0.2 t = 0.5 t = 0.8
b = 0 b = 0.05 b = 0.1 b = 0 b = 0.05 b = 0.1 b = 0 b = 0.05 b = 0.1
θ1 = 0.05, θ2 = 0.05
Mean bias 0.0239 0.0291 0.0336 0.0326 0.0453 0.0608 0.0386 0.0568 0.0807
Pr(dS ≽ b) 0.78 0.67 0.53 0.84 0.67 0.45 0.87 0.67 0.40
Pr(S = 1 | dS ≽ b) 0.49 0.50 0.50 0.50 0.49 0.50 0.50 0.50 0.51
Pr(S = 1,d2 ≽ b) 0.29 0.25 0.21 0.33 0.25 0.19 0.34 0.25 0.16
Pr(S = 2,d1 ≽ b) 0.30 0.24 0.21 0.32 0.26 0.18 0.34 0.25 0.16
θ1 = 0.05, θ2 = 0.05
Mean bias 0.0244 0.0293 0.0354 0.0360 0.0467 0.0631 0.0411 0.0615 0.0856
Pr(dS ≽ b) 0.76 0.64 0.50 0.80 0.62 0.41 0.83 0.61 0.34
Pr(S = 1 | dS ≽ b) 0.44 0.43 0.41 0.40 0.39 0.38 0.37 0.36 0.34
Pr(S = 1,d2 ≽ b) 0.26 0.22 0.17 0.26 0.19 0.14 0.26 0.17 0.11
Pr(S = 2,d1 ≽ b) 0.30 0.26 0.21 0.36 0.26 0.18 0.39 0.26 0.16