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Box plot of normalized total toxicity profile (nTTP) and dose-limiting toxicity (DLT) distribution for the quasi-likelihood continual reassessment method (QLCRM), quasi-continual reassessment method (QCRM), extended isotonic design (EID) method, and unified approach (UA) method. We define the minimum whisker as Q1 − 1.5 * IQR and the maximum whisker as Q3 + 1.5 * IQR; Q1 and Q3 are the first and third quartiles, respectively.
