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. 2013 Oct 28;13:288. doi: 10.1186/1472-6882-13-288

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Copyright © 2013 Yang et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effects of EA on stem cell proliferation in the hippocampal dentate gyrus (DG) after 4 weeks. (A) Representative triple immunofluorescence staining for BrdU + (red), Sox2+ (green) and Hoechst (blue) in the central region of the DG. Scale bar = 100 μm. (B) Quantitative representation of Sox2/BrdU double-positive cells in the DG zone (not only those regions in A) per section. EA treatment significantly improved the stem cell proliferation compared with the CUS Model. The values are the mean ± SE, n = 5 in each group. ** P <0.01 (Model vs. Normal); # P <0.05 (EA vs. Model).