Multiple hybrid three-dimensional renderings of the 8-animal cohort at baseline. In each case, color contouring, which is determined by septolateral two-dimensional leaflet curvatures, has been superimposed across a 1.0-mm wide-septolaterally oriented segment of the mitral valve (anterior and posterior leaflets). (A) This is a transvalvular (xy) view of the rendering. (B) The same view is illustrated where the medial hemi-valve is transparent. (C) This is an oblique view of the rendering where the medial hemi-valve is transparent; in this case, the relationship between curvature sign and surface concavity/convexity is readily apparent. The midanterior annulus (mid-AA), midposterior annulus (mid-PA), anterior commissure (AC), and posterior commissure (PC) have been labeled in each view.