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. 2013 Oct 7;2013:565431. doi: 10.1155/2013/565431

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Copyright © 2013 Yuan Hung Lo et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Parameter sensitivity analysis of APD₆₀, Δ[Ca]_i, Δ[Ca]_SL, and Δ[Ca]_jct sensitivities toward 10% increases in maximal transporters' conductance and permeability. Positive value indicates direct relationship between parameter and output (e.g., enhanced L-type Ca²⁺ permeability prolongs APD₆₀), and negative value indicates indirect relationship between parameter and output. Nimrod/E-Lenth plots (left column), PLS-bar plots (right column). Nimrod/E analysis produced similar qualitative results as PLS analysis.