Table 3.

Diffusion coefficients varied in the model.

Definition		Symbol	Baseline value
1	Diffusion coefficient for Ca2+ from junctional cleft to SL compartment	D Ca(jct-SL)	1.64 10−6 cm2/s
2	Diffusion coefficient for Ca2+ from SL compartment to bulk cytosol	D Ca(SL-i)	1.22 10−6 cm2/s
3	Diffusion coefficient for Na+ from junctional cleft to SL compartment	D Na(jct-SL)	1.09 10−5 cm2/s
4	Diffusion coefficient for Na+ from SL compartment to bulk cytosol	D Na(SL-i)	1.79 10−6 cm2/s

Notes: in the Shannon et al. article [1] D _{Ca(junction-SL)} corresponds to   D _Ca(jct-SL),   D _{Ca(SL-cytosol)}  to  D _Ca(SL-i),  D _{Na(junction-SL)}  to D _Na(jct-SL), and D _{Na(SL-cytosol)} to D _Na(SL-i). The baseline diffusion coefficients values used in this study are the same as in [1].