Table 2.
Changes in surface marker expression throughout the mouse primitive erythroid lifespan.
| Surface protein | Early EryP-CFC (E7.5) |
EryP-CFC (E8.5) |
Early circulating EryP (E9.0-11.5) | Late circulating EryP (E11.5>) |
Fetal liver EryP | Primitive retics. |
|---|---|---|---|---|---|---|
| Flk1 | ++ | — | — | — | ND | — |
| CD144/VE-cadherin | ++ | — | — | — | ND | — |
| Tie2 | +++ | ++++ | — | — | ND | ND |
| Endoglin | +++ | ++++ | — | — | — | — |
| CD31/PECAM | ++++ | ++++ | — | — | ND | — |
| CD41 | ++++ | ++++ | — | — | — | — |
| c-Kit | +++ | ++++ | — | — | — | — |
| CD71 | ND | ND | ++++ | +++ | +++ | + |
| Ter-119 | — | — | ++ | ++++ | ++++ | +++ |
| CD9 | ND | ND | ++++ | ++++ | ++++ | — |
| CD24 | ND | ND | ++++ | ++++ | ND | ND |
| CD55 | ND | ND | ++++ | ++++ | ND | ND |
| CD147/Basigin | ND | ND | ++++ | ++++ | ND | ++++ |
| a4 integrin | ++++ | ++++ | — | + | ++++ | — |
| a5 integrin | ++++ | ++++ | — | + | ++++ | — |
| b1 integrin | ++++ | ++++ | — | + | ++++ | — |
| CD44 | ++++ | ++++ | — | + | ++++ | — |
| CXCR7 | ND | ND | — | +++ | ND | ND |
+Indicate relative levels of surface expression. References included in main body of text.