Table 1.
Variables | 1st Quartile n = 102 | 2nd Quartile n = 103 | 3rd Quartile n = 103 | 4th Quartile n = 102 | P valuea |
---|---|---|---|---|---|
Clinical characteristics | |||||
Age (years) | 67 ± 0.8 | 69 ± 0.8 | 69 ± 0.8 | 69 ± 0.8 | <0.001 |
Women (%) | 79 | 60 | 41 | 14 | <0.001 |
Weight (lbs) | 71 ± 1.1 | 83 ± 1.2 | 89 ± 1.4 | 103 ± 1.4 | <0.001 |
Height (in) | 165 ± 0.8 | 169 ± 0.9 | 170 ± 0.9 | 174 ± 1.0 | <0.001 |
BMI (kg/m2) | 27 ± 0.6 | 30 ± 0.6 | 31 ± 0.7 | 34 ± 0.6 | <0.001 |
BP diastolic (mm Hg) | 77 ± 1.2 | 75 ± 1.3 | 76 ± 1.4 | 81 ± 1.3 | 0.10 |
BP systolic (mm Hg) | 142 ± 2.1 | 139 ± 2.4 | 139 ± 2.2 | 144 ± 2.3 | 0.07 |
Heart rate (beats/min) | 68 ± 1.7 | 66 ± 1.5 | 64 ±1.4 | 67 ± 1.3 | 0.52 |
Diabetes (%) | 34 | 36 | 42 | 44 | 0.03 |
Hypertension (%) | 89 | 90 | 90 | 93 | 0.39 |
Hypercholesterolemia (%) | 66 | 69 | 71 | 82 | 0.03 |
Smokers (%) | 44 | 54 | 42 | 58 | 0.13 |
CAD (%) | 21 | 30 | 30 | 33 | 0.11 |
Laboratory characteristics | |||||
CRP (mg/l) | 2.2 ± 0.6 | 3.2 ± 0.5 | 5.6 ± 1.1 | 3.5 ± 0.5 | < 0.22 |
Glucose (mg/dl) | 107 ± 3 | 117 ± 5 | 124 ± 6 | 124 ± 5 | 0.005 |
Total cholesterol (mg/dl) | 179 ± 5 | 171± 8 | 163 ± 6 | 170 ± 6 | 0.06 |
HDL-C (mg/dl) | 56 ± 2 | 50 ± 2 | 44 ± 2 | 39 ± 1 | <0.001 |
LDL-C (mg/dl) | 102 ± 4 | 94 ± 7 | 100 ± 8 | 115 ± 13 | 0.03 |
TG (mg/dl) | 102 ± 7 | 126 ± 11 | 124 ± 10 | 165 ± 11 | <0.001 |
All data expressed as mean ± s.e. of mean (s.e.m.).
BP blood pressure; CAD, coronary artery disease; CRP, C-reactive protein; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; TG, triglycerides.
Based on linear regression for continuous variables and χ2 for dichotomous variables.