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. Author manuscript; available in PMC: 2013 Oct 31.
Published in final edited form as: J Control Release. 2011 Dec 2;160(2):10.1016/j.jconrel.2011.11.030. doi: 10.1016/j.jconrel.2011.11.030

Fig. 3.

Fig. 3

Gene knockdown capacity of alkylated PEI compounds. RNAi and cell viability were tested in HeLa cells that express both Renilla and firefly luciferase. (A) Lipid–PEI compounds were complexed with anti-firefly siRNA and then incubated with the cells. Mean knockdown levels increased as the number of lipid tails conjugated to the PEI increased. (B) Cell viability was measured by recording the expression of an off-target gene — Renilla luciferase and is relative to non-treated cells. In both graphs error bars represent the standard deviation (N=8).