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. Author manuscript; available in PMC: 2013 Oct 31.
Published in final edited form as: J Control Release. 2011 Dec 2;160(2):10.1016/j.jconrel.2011.11.030. doi: 10.1016/j.jconrel.2011.11.030

Fig. 5.

Fig. 5

Binding affinity between alkane-modified PEI to siRNA. PEI with higher conjugation levels had weaker binding affinity to siRNA in comparison to lower conjugation levels. This was noticed when testing the affinity between modified PEI to siRNA at various N/P ratios (A), and after incubating siRNA-complexed particles with heparin sodium salt (Sigma) at various concentrations (B). Bands represent free (non-bound) siRNA as detected on an agarose gel.