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. Author manuscript; available in PMC: 2013 Oct 31.
Published in final edited form as: Anticancer Agents Med Chem. 2011 May 1;11(4):359–372. doi: 10.2174/187152011795677490

Fig 4. Dose-dependent mitigation of respiratory chain effects in irradiated astrocytes by EUK-134.

Fig 4

Rat astrocytes were cultured and exposed to ionizing radiation as described for Fig. 3. EUK-134 was added immediately after irradiation, where indicated. On day 4 after irradiation, cells were harvested and respiratory chain complex activities measured as previously described for Complex I [104], Complex II [105], and Complex III [106]. Y axis indicates percent of the activity of the unirradiated control cells. Data are means ± SEM for n=3. ** indicates significantly different from unirradiated (no EUK-134); * indicates significantly different from 30 Gy (no EUK-134) (p<0.05).