Skip to main content
. Author manuscript; available in PMC: 2013 Oct 31.
Published in final edited form as: Curr Drug Targets. 2010 Nov;11(11):1423–1429. doi: 10.2174/1389450111009011423

Fig. 4.

Fig. 4

Mitigation of radiation-induced azotemia (as BUN) 17 weeks after TBI plus BMT in a rat model. Data is shown as geometric means with 95% confidence intervals. One group of rats received 19 Gy fractionated TBI plus L-155809 (an AT1 receptor blocker) at 20 mg/l in their drinking water, or a high-salt (8% NaCl) or normal-salt (0.5% salt) diet; drug therapy started within 24 hours after TBI and continued for 10 weeks. A second group of rats received a single 10 Gy TBI dose and an ACE inhibitor (captopril) at 150 mg/l in their drinking water, or high-salt (4% or 8%) diets. Drug therapy started 7 days after TBI and continued for 9 weeks.