Skip to main content
. 2013 Oct 9;5(10):2008–2018. doi: 10.1093/gbe/evt151

Fig. 1.—

Fig. 1.—

The two domains of Oct1 (POUS [bottom right] and POUHD [top right]) and the SOX2 (left) transcription factors bind adjacently to the Hoxb1 element on DNA. Sox2 and POUS interact by binding cooperatively to adjacent sites to facilitate the binding of co-activator OBF-1 (Williams et al. 2004). The image is generated from PDB file 1O4X.