Skip to main content
. 2013 May 13;68(12):1458–1468. doi: 10.1093/gerona/glt044

Table 2.

Main Effects of Age and Training on Neuromuscular Junctions in the Lateral Thyroarytenoid Muscle

Young Old Control Trained
Presynaptic remodelling
Axon withdrawal (%) 39.9±4.6 40.9±5.2 37.9±4.2 43.0±5.5
Axon sprouts (%)* 2.3±0.8 9.0±2.3 4.4±1.7 6.9±2.0
Terminal Schwann cell processes (%) 14.3±2.5 19.9±3.7 17.6±3.2 16.7±3.3
Size and pre/postrelationship
Nerve terminal volume (µm3) 76.6±8.9 74.4±9.5 63.4±7.3 87.6±10.0
Motor endplate volume (µm3) 224.4±8.5 247.9±8.4 230.1±11.1 242.3±5.6
Overlap (%) 33.9±4.3 34.3±4.7 33.1±4.1 35.1±4.9
Endplate stability
Dispersion (%) 10.9±0.5 13.5±0.7§ 12.4±0.9 11.9±0.4§
Fragmented endplates (%) 11.6±1.4 28.7±2.5 20.7±3.2 19.6±2.4

Notes: Values are means ± SE; n = 40 (20 per group).

*Nonparametric testing completed due to heteroskedasticity.

Significant difference (p ≤ .05) from young group.

Log transformed to achieve homoskedasticity; values shown untransformed.

§Significant interaction (p ≤ .05) between age and training.