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. 2013 Oct 8;47(4):330–337. doi: 10.2478/raon-2013-0063

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Copyright © by Association of Radiology & Oncology

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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FIGURE 3. — bFGF stimulates growth of GSCs. Growth curves of cells cultured in stem cell media differing in the presence of EGF and/or bFGF. Both cell lines showed the fastest growth upon bFGF stimulation, either alone or in complete medium with both growth factors whereas EGF alone did not significantly stimulate cell growth compared to medium without growth factors. Labels: NB=plain Neurobasal medium without growth factors; compl=NB with EGF and bFGF; EGF=NB with EGF; bFGF=NB with bFGF. Data shown are mean ± SD of three independent experiments with the following significant changes: ****: p<0,0001 for NCH421k (NB vs compl, NB vs bFGF, EGF vs compl, EGF vs bFGF); ***: p<0,001 for NCH644 (NB vs compl, NB vs bFGF, EGF vs compl, bFGF vs compl, EGF vs bFGF).