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Efficiency of CRISPR–Cas-induced mutations. (A–D) Mutations induced by CRISPR–Cas9 using targeting sequences for ben-1 (A and B), unc-4 (C) and unc-5 (D). For ben-1a, only a subset of the mutations we obtained is shown. (E) Efficiency of CRISPR-induced mutagenesis at different loci.
