Figure 3.

miR-210 expression is up-regulated in maternal serum in hypertensive disorders of pregnancy. A: Relative serum expression of miR-210 in case-control study (third trimester). Points represent individual samples. Black horizontal lines are the medians of the respective groups. The median of the control group is set to 1. B: Receiver-operator curve (ROC) showing specificity and sensitivity of miR-210 as a classifier for the disease state. C and D: Similar to A and B, but with second-trimester serum samples. ROC curves in B and D are corrected for maternal age, BMI, race, and parity.