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. 2013 Nov;183(5):1498–1507. doi: 10.1016/j.ajpath.2013.07.019

Figure 1.

Figure 1

Role of IL-17A in the development of hepatocellular injury after BDL. A: IL-17A mRNA levels were quantified by real-time PCR in the livers of mice subjected to BDL for the indicated times.∗P < 0.05 versus day 0. Mice were treated with either an anti–IL-17A antibody or isotype control. The mice were then subjected to BDL or sham operation. Alanine aminotransferase (ALT) activity (B) and percentage area of liver necrosis (C–E) were quantified 9 days after surgery. Scale bars: 100 μm. †P < 0.05 versus sham-operated mice; ‡P < 0.05 versus isotype control BDL mice. Data are given as means ± SEM.