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. 2013 Nov 1;4:318. doi: 10.3389/fphys.2013.00318

Figure 2.

Figure 2

Schematic view of PSCs' multifaceted roles in modulating cell-to-cell interactions. Activated PSCs, mast cells, and MDSCs foam complex network that modify tumor microenvironment. CSCs, cancer stem cells; EMT, epithelial-mesenchymal transition; MDSCs, myeloid-derived suppressor cells; PSCs, pancreatic stellate cells; ROS, reactive oxygen species.