Table 1.
Type of cell | Uninfected lungs | B6-infected lungs | Il10−/−-infected lungs |
---|---|---|---|
CD4+ IL-17+ T cells | 1.8 × 104 ± 6 × 103 | 2.4 × 105 ± 9.2 × 104∗ | 4.2 × 105 ± 1.5 × 104† |
γδ+ IL-17+ T cells | 1.2 × 104 ± 6.2 × 103 | 1.7 × 105 ± 7.4 × 104∗ | 2.9 × 105 ± 6.1 × 104† |
B6 and Il10−/− mice were left uninfected or were infected with 1000 CFUs F. tularensis LVS intratracheally. On day 6, single-cell lung suspensions were assayed for IL-17 production by intracellular staining and flow cytometry.
P ≤ 0.005 between B6-infected and uninfected mice.
P ≤ 0.05 between B6-infected and Il10−/−-infected mice.