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. 2013 Nov;183(5):1405–1410. doi: 10.1016/j.ajpath.2013.07.007

Figure 1.

Figure 1

A: Correspondence analysis of miRNAs in ALI cultures and in vivo airway epithelium. In this unsupervised analysis based on all detectable human miRNAs, global variability in miRNA expression distinctly segregated in vivo samples (n = 11) from in vitro cultures (n = 8). B: Differentially regulated miRNAs between ALI cultures and in vivo airway epithelium. Heat-map depiction of 100 highly differentially expressed miRNAs between the in vitro and in vivo groups (q < 0.001). Gray color indicates miRNA levels undetectable by PCR. C: Correspondence analysis of microarray-based gene expression in ALI cultures and in vivo airway epithelium. In this analysis based on the expression profile of more than 5000 genes, global variability in gene expression clearly discriminated between in vivo samples and in vitro cultures. n = 16 samples per group.