Table 2.

HLA haplotype of patients CIN BEN-like and daily intake of OTA for the subjects calculated from the plasma clearance, blood concentration and bioavailability of OTA in human according to the following equation, $\text{K}=\text{Cpl}\times \text{Cp}/\text{A}$ in which K= daily intake, Cpl= OTA plasma clearance ml/min, Cp=OTA plasma concentration and A= bioavailability.

	Case N°	OTA in Food μg/kg	OTA in Blood/ng/ml	OTA Daily intake ng/kg bw/Day	CIN BEN-Like	HLA Determinant
Family I	1	0.88 ± 0.45	505.8	658	+	A3/28; B 27/35; DR 7/52
	2		102.4	133	+	A3/28; B 27/35; DR 7/11
	3		1023	1330	+	A3/40; B 27/35; DR 7/52
	4		378	491	−
	5		20.4	27	−
	6		0	0	−
	7		1332	1732	−
	8		15	20	−
Family II	9	5.29 ±7.19	1348	1752	−
	10		702	912.6	−
	11		1334	1734	−
	12		8	10.4	−
	13		15	20	−
Family III	14	0.94 ± 0.45	967	1257	−
	15		218	283	−
	16		210	273	−
	17		33	42.9	−
	18	0.31 ± 0.21	0	0	−
	19		9	12	−
	20	ND	268	348	−
	21		8	10	−