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. 2013 Sep 12;122(18):3138–3148. doi: 10.1182/blood-2012-12-474056

Table 2.

Patient characteristics and CD123 expression of primary AML patient samples

AML sample ID Age/sex Cytogenetics Flt3 mutational status Clinical status at time of sample collection Sample type CD123 (RFI)* CD123% positive
179 74/M Intermediate risk, t(1;7), t(14;15) ND Relapsed PB 428.32 99.22
373 47/M Poor risk, complex abnormalities in 3 cell lines ND Relapsed PB 1052.83 99.66
493 46/F Intermediate risk, trisomy 8 ND Relapsed PB 23.98 76.80
519 44/F del(17p), dic (11;7), clonal loss of TP53/17p13.1 ND Relapsed PB 63.18 97.40
545 58/M Intermediate risk, t(3;6), del(7) ND Induction failure PB 52.73 99.32
559 59/M Complex abnormalities, massive hyperdiploidy Negative Relapsed Apheresis 9.30 45.0
605 55/M Normal Negative Persistent PB 58.48 99.91
722 22/M Intermediate risk, t(14;21), del(9q) Negative Untreated PB 33.53 92.74
813 48/F Complex abnormalities, trisomy 8, trisomy 21, add(17) ND Untreated PB 37.19 90.93

F, female; M, male; ND, not determined; PB, peripheral blood.

*

RFI is the ratio of the median of the anti-CD123 antibody (clone 9F5)-stained signal to isotype-matched control stain in the CD34+ population.

Gated on CD34+ population.