Table 2.
AML sample ID | Age/sex | Cytogenetics | Flt3 mutational status | Clinical status at time of sample collection | Sample type | CD123 (RFI)* | CD123% positive† |
---|---|---|---|---|---|---|---|
179 | 74/M | Intermediate risk, t(1;7), t(14;15) | ND | Relapsed | PB | 428.32 | 99.22 |
373 | 47/M | Poor risk, complex abnormalities in 3 cell lines | ND | Relapsed | PB | 1052.83 | 99.66 |
493 | 46/F | Intermediate risk, trisomy 8 | ND | Relapsed | PB | 23.98 | 76.80 |
519 | 44/F | del(17p), dic (11;7), clonal loss of TP53/17p13.1 | ND | Relapsed | PB | 63.18 | 97.40 |
545 | 58/M | Intermediate risk, t(3;6), del(7) | ND | Induction failure | PB | 52.73 | 99.32 |
559 | 59/M | Complex abnormalities, massive hyperdiploidy | Negative | Relapsed | Apheresis | 9.30 | 45.0 |
605 | 55/M | Normal | Negative | Persistent | PB | 58.48 | 99.91 |
722 | 22/M | Intermediate risk, t(14;21), del(9q) | Negative | Untreated | PB | 33.53 | 92.74 |
813 | 48/F | Complex abnormalities, trisomy 8, trisomy 21, add(17) | ND | Untreated | PB | 37.19 | 90.93 |
F, female; M, male; ND, not determined; PB, peripheral blood.
RFI is the ratio of the median of the anti-CD123 antibody (clone 9F5)-stained signal to isotype-matched control stain in the CD34+ population.
Gated on CD34+ population.