TABLE 1.

Crystallographic data collection and refinement statistics

Data collection
Space group	I 41 2 2
Cell dimensions, a, b, c (Å)	117.80, 117.80, 103.46
Resolution (Å)	46.95-2.89 (3.05-2.89)
Rmerge	0.128 (0.839)
I/σI	9.8 (2.3)
Completeness (%)	99.8 (99.5)
Redundancy	6.3 (6.4)
Refinement
Resolution (Å)	83.30-2.89
No. reflections	7765
Rwork/Rfree	20.3/22.6
No. atoms
Protein	1139
Ligand	36
B-Factors (Å2)
Wilson	81.3
Average of atoms	53.1
r.m.s.d.
Bonds (Å) r.m.s.d./r.m.s.Z	0.018/0.945
Angles (°) r.m.s.d./r.m.s.Z	2.296/1.048
Validation (Molprobity)
Ramachandran favored	100%
Ramachandran outliers	0%
MolProbity score	1.95