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. 2013 Nov;23(11):1852–1861. doi: 10.1101/gr.157388.113

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© 2013 Vieira et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 2. — Effect of the inbreeding coefficient on genotype calling. Performance of genotype calling globally (left column), on just heterozygous genotypes (center column) and just homozygous genotypes (right column), on a sample size of 10 (first row) and 30 (second row) individuals and 10,000 variable sites simulated with a 0.5% error rate. Line styles and symbols represent different simulated sequencing coverages. Line types represent the level of inbreeding assumed in the priors: F = 0 (HWE; filled) and inferred value of F (Infer. F; large dashes). Missing F = 1 values reflect the absence of heterozygous genotypes on a totally inbred sample.