Table 2. Possible additional glycosomal membrane proteins.
This list includes all detected proteins with predicted trans-membrane (TM) domains, for which there is no evidence for location in any particular compartment.
| Lta gene ID | Pep nr | Cov (%) | Tb gene ID | Function | TMs (a) | TMs (b) | ER sp |
|---|---|---|---|---|---|---|---|
| LtaP29.1650 | 3 | 3 | Tb927.3.4070 Tb927.3.4110 | Major facilitator family, nitrate and chloride transporter? | 12 | nd | no |
| LtaP01.0560 | 4 | 17 | Tb927.9.4310 | putative tricarboxylate carrier, matches yeast putative alpha-isopropylmalate carrier, which exports alpha-isopropylmalate from the mitochondrion to the cytoplasm for use in leucine biosynthesis | 5 | nd | no |
| LtaP05.0670 | 2 | 6 | Tb927.9.4310 | putative tricarboxylate carrier, matches yeast putative alpha-isopropylmalate carrier, which exports alpha-isopropylmalate from the mitochondrion to the cytoplasm for use in leucine biosynthesis | 5 | nd | no |
| LtaP36.4130 | 3 | 6 | Tb927.11.10260 | hypothetical protein, conserved | 0 | 2 | no |
| LtaP33.2680 | 4 | 4 | Tb927.11.2590 | hypothetical protein, conserved | 0 | 2 | no |
| LtaP29.0320 | 2 | 21 | Tb927.3.5350 | hypothetical protein, conserved | 1 | 1 | no |
| LtaP36.6980 | 4 | 4 | Tb927.10.8000 | P-loop nucleoside triphosphate hydrolase, contains EF hand domains | 0 | 1 | no |
| LtaP21.0440 | 4 | 6 | Tb927.10.2240 | NTF2-like domain | 0 | 1 | no |
| LtaP11.1210 | 2 | 5 | Tb927.11.6070 | ARM repeat superfamily | 0 | 1 | no |
| LtaP31.3020 | 2 | 3 | Tb927.4.5000, Tb927.8.7420 | TERD-like domains | 0 | 1 | yes |
| LtaP35.4380 | 2 | 4 | Tb927.9.10470 | hypothetical protein, conserved | 0 | 1 | no |
| LtaP34.2250 | 2 | 5 | Tb927.4.2250 | hypothetical protein, conserved | 0 | 1 | no |
| LtaP06.1080 | 3 | 11 | Tb927.7.5700 | hypothetical protein, conserved | 1 | nd | yes |
| LtaP26.0630 | 3 | 12 | Tb927.7.1290 | hypothetical protein, DUF2012, peptidase superfamily, starch binding domain, similarity to human C15ORF24 | 1 | nd | yes |
| LtaP36.3480 | 2 | 8 | Tb927.11.10040 | hypothetical protein, conserved | 1 | nd | no |
| LtaP17.1410 | 2 | 36 | Tb927.5.2560 | hypothetical protein, conserved | 1 | nd | no |
| LtaP23.0390 | 3 | 10 | Tb927.8.2300 | hypothetical protein, conserved | 1 | nd | no |
Abbreviations used: Lta, Leishmania tarentolae; Tb, Trypanosoma brucei; Pep nr, number of identified peptides; Cov (%), percentage of protein coverage; TMs (a), number of annotated trans-membrane domains; TMs (b), number of transmembrane-domains identified by THMM TOP; ER sp, endoplasmic reticulum signal peptide.