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. 2013 Oct 28;72(11):1016–1028. doi: 10.1097/NEN.0000000000000000

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Copyright © 2013 by the American Association of Neuropathologists, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.

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Thy1.2-hNIPA1^G106R rat morphology. (A) A neurite within the anterior horn of the lumbar cord of a 12-week-old Thy1.2-hNIPA1^G106R rat showing a partially digested large aggregate of a tubulovesicular structure within an autophagic vacuole. Scale bar = 2 μm. (B) Higher magnification shows the elongated tubular morphology of these aggregates. Arrow indicates the remnants of the surrounding double membrane. Scale bar = 100 nm.