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. 2013 Sep 13;3:311–320. doi: 10.1016/j.nicl.2013.09.002

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© 2013 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig. 4 — Behavioral significance of the bilateral hippocampal functional connectivity networks across all subjects (p < 0.05, AlphaSim correction). Top row: Main effects of the depressive symptoms on the bilateral HFC networks; Middle row: Main effects of the episodic memory scores (LMIIDR scores) on the bilateral HFC networks. Bright color indicates positive correlation and blue color indicates negative correlation; Bottom row: Interaction of depressive symptoms and memory function on the bilateral HFC networks. Bright color indicates that the interactive effects are positively correlated with bilateral HFC; blue color demonstrates that the interactive effects are negatively correlated with bilateral HFC. Color bar is presented with z scores.

Abbreviations: GDS, geriatric depression scale; LHFC, left hippocampal functional connectivity; RHFC, right hippocampal functional connectivity; LDLPFC, left dorsolateral prefrontal cortex; RDLPFC, right dorsolateral prefrontal cortex; LDMPFC, left dorsomedial prefrontal cortex; RDMPFC, right dorsomedial prefrontal cortex; LITC, left inferior temporal cortex; RITC, right inferior temporal cortex; LHip/PHG, left hippocampus/parahippocampal gyrus; RHip/PHG, right hippocampus/parahippocampal gyrus; LIPC, left inferior parietal cortex; RIPC, right inferior parietal cortex; LaI/fO, left anterior insula/frontal operculum; RaI/fO, right anterior insula/frontal operculum; LIFG, left inferior frontal gyrus; LTha, left thalamus; L Pcu/PCG, precuneus/postcentral gyrus; Pcu/PCG, precuneus/postcentral gyrus; vmPFC, ventromedial prefrontal cortex; Amy/PHG, amygdala/parahippocampal gyrus; RpMTG, right posterior middle temporal gyrus. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)