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. 2013 Sep 12;1(1):441–445. doi: 10.1016/j.redox.2013.08.006

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© 2013 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig. 2 — Nrf2 activators increase extracellular CysGly levels. U373 cells were treated with R-lipoic acid (LA), tert-butylhydroquinone (TBHQ), sulforaphane (SFN) or Polygonum cuspidatum containing 50% resveratrol (PC-Res) for 48 h. The concentration of cysteinylglycine (CysGly) in the media was then determined by HPLC with fluorescence detection. Data points represent mean values from three independent experiments, while error bars represent SD. ^⁎ and ^⁎⁎⁎ designate significant differences (p<0.05 and p<0.001) to the non-treated control.