Table 2.
Cortical area | Mean (SD) in mm |
PTSD vs. non-PTSD |
PTSD vs. Healthy |
|||||
---|---|---|---|---|---|---|---|---|
Side | PTSD (n = 15) |
Non-PTSD (n = 10) |
Healthy (n = 25) |
T value | P value | T value | P value | |
Cortical thickness decreasing (PTSD < control) | ||||||||
Superior frontal gyrus | Left | 2.389 (0.128) | 2.422 (0.125) | 2.609 (0.251) | − 3.615 | 0.022 | − 4.835 | 0.008 |
Right | 2.411 (0.247) | 2.477 (0.148) | 2.543 (0.268) | − 2.669 | 0.036 | − 4.203 | 0.013 | |
Rostral middle frontal gyrus | Left | 2.147 (0.220) | 2.157 (0.196) | 2.252 (0.181) | − 1.644 | NS | − 1.863 | NS |
Right | 2.199 (0.217) | 2.228 (0.234) | 2.331 (0.195) | − 2.293 | 0.042 | − 3.301 | 0.032 | |
Hippocampal gyrus | Left | 2.291 (0.208) | 2.457 (0.215) | 2.549 (0.169) | − 3.202 | 0.028 | − 4.141 | 0.014 |
Right | 2.361 (0.141) | 2.523 (0.224) | 2.610 (0.145) | − 3.914 | 0.019 | − 4.635 | 0.009 | |
Inferior parietal lobes | Left | 2.678 (0.175) | 2.826 (0.186) | 2.922 (0.201) | − 2.845 | 0.033 | − 4.843 | 0.007 |
Right | 2.692 (0.177) | 2.728 (0.182) | 2.812 (0.159) | − 2.323 | 0.041 | − 2.684 | 0.035 | |
Superior parietal lobes | Left | 2.254 (0.144) | 2.318 (0.145) | 2.368 (0.137) | − 1.093 | NS | − 2.963 | 0.033 |
Right | 2.322 (0.109) | 2.421 (0.157) | 2.468 (0.127) | − 1.527 | NS | − 3.307 | 0.032 | |
Lateral occipital gyrus | Left | 2.815 (0.284) | 2.874 (0.267) | 2.941 (0.297) | − 1.368 | NS | − 1.788 | NS |
Right | 2.554 (0.285) | 2.649 (0.253) | 2.757 (0.313) | − 3.048 | 0.032 | − 2.534 | 0.040 | |
Anterior cingulate cortex (ACC) | Left | 2.721 (0.224) | 2.961 (0.219) | 3.080 (0.344) | − 3.755 | 0.028 | − 3.409 | 0.029 |
Right | 2.628 (0.335) | 2.882 (0.224) | 2.972 (0.348) | − 3.643 | 0.021 | − 4.083 | 0.017 | |
Posterior cingulate cortex (PCC) | Left | 2.601 (0.113) | 2.756 (0.141) | 2.771 (0.189) | − 3.286 | 0.029 | − 3.309 | 0.031 |
Right | 2.607 (0.157) | 2.715 (0.115) | 2.799 (0.168) | − 3.048 | 0.032 | − 3.443 | 0.025 | |
Cortical thickness thickening (PTSD > control) | ||||||||
Calcarine gyrus | Left | 2.536 (0.301) | 2.517 (0.388) | 2.461 (0.253) | 2.058 | 0.047 | 4.426 | 0.011 |
Right | 2.586 (0.240) | 2.563 (0.333) | 2.517 (0.254) | 1.579 | NS | 1.692 | NS |
PTSD, post-traumatic stress disorder; SD, standard deviation. Results significant at false discovery rate threshold 0.05; NS: not significant.