Table 3.
Brain regions activated during the Response to Outcome interval.
| Anatomic location of maximum activation | MNI coordinates |
T score | ||
|---|---|---|---|---|
| x | y | z | ||
| Mentalizing Network | ||||
| Human Show > No-Show masked with Human > Computer (all subjects) | ||||
| L TPJ (ITS/MTG/STS) | − 54 | − 60 | 9 | 6.66 |
| R TPJ (ITS/MTG/STS) | 57 | − 48 | 12 | 6.40 |
| L TP | − 39 | 18 | − 30 | 3.40 |
| R TP | 36 | 18 | − 39 | 3.52 |
| R FG | 45 | − 45 | − 18 | 5.26 |
| MPFC | 0 | 42 | 12 | 3.75 |
| PCC | 9 | − 45 | 39 | 3.99 |
| R VLPFC | 51 | 15 | 36 | 5.74 |
| L Putamen | − 21 | 9 | − 15 | 4.00 |
| R Putamen | 15 | 12 | − 6 | 3.18 |
| Healthy Controls > ASD individuals | ||||
| L MTG | − 60 | − 45 | − 3 | 2.54 |
| R MTG | 57 | − 30 | − 12 | 3.20 |
| Reward-related Motivation Network | ||||
| Gains > Losses (all subjects) | ||||
| L NAcc | − 12 | 15 | − 3 | 4.19 |
| R NAcc | 18 | 12 | − 9 | 5.10 |
| L MFG (BA 6) | − 30 | − 6 | 57 | 4.55 |
| R MFG (BA 6) | 33 | 3 | 57 | 5.33 |
| L SPL | − 39 | − 48 | 57 | 5.18 |
| R SPL | 42 | − 30 | 42 | 5.10 |
| Healthy Controls > ASD individuals | ||||
| R NAcc | 15 | 15 | − 9 | 3.07 |
BA, Brodmann region; FG, fusiform gyrus; ITS, inferior temporal sulcus; MFG, middle frontal gyrus; MPFC, medial prefrontal cortex; MTG, middle temporal gyrus; NAcc, nucleus accumbens; OFC, orbitofrontal cortex; PCC, posterior cingulate cortex; SPL, superior parietal lobule; STS, superior temporal sulcus; TP, temporal pole; TPJ, temporoparietal junction; VLPFC, ventrolateral prefrontal cortex; L, left; R, right.