Figure 2.

Genes significantly correlated with ear and articular cartilage healing phenotypes. Knee joint tissues from FFPE sections were macrodissected and tissue homogenates were prepared. The gene expression levels were quantified through QuantiGene Plex assay and were correlated with ear and articular cartilage healing scores. Five genes, namely Axin2, Wnt16, Pcna, Xrcc2, and Il6, were found to be significantly positively correlated with ear wound healing, whereas Map1lc3a was significantly negatively correlated with ear wound healing (A–F). Similarly, five genes, namely Axin2, Wnt16, Pcna, Xrcc2, and Ulk1, were found to be significantly positively correlated, whereas Cebpb was significantly negatively correlated with articular cartilage healing (G–L). r = Pearson correlation coefficient.