Table 3. Study of the variability and hydrophobicity of the different CT regions of HIV-2.
Region (CT aa positions) | Average SE | Average mixture of aa per position | Kyte-Doolittle scale score average | Average variation per position per alignment** | Average SE provius alignment/ virus alignment* |
---|---|---|---|---|---|
CT (1 to 165) | 0.618 | 0.570 | -0.295 | 0.511 | 0.229/0.200 |
A (0 to 20) | 0.253 | 0.15 | -0.616 | 0.250 | 0.121/0.068 |
B (21 to 47) | 0.898 | 1.11 | -1.813 | 0.889 | 0.360/0.283 |
B group A* | 0.278 | ND | ND | ND | ND |
B group B* | 0.193 | ND | ND | ND | ND |
C (48 to 68) | 0.504 | 0.428 | 1.190 | 0.333 | 0.192/0.152 |
D (69 to 91) | 0.807 | 0.957 | 0.023 | 0.479 | 0.232/0.252 |
E (92 to 125) | 0.565 | 0.324 | -0.195 | 0.441 | 0.189/0.208 |
F (126 to 136) | 0.691 | 0.364 | -0.495 | 0.272 | 0.292/0.216 |
G (137 to 165) | 0.592 | 0.517 | -0.032 | 0.724 | 0.228/0.191 |
G start (137 to 150) | 0.968 | 1.071 | 0.216 | 1.286 | 0.360/0.312 |
G end (151 to 165) | 0.242 | 0.067 | -0.382 | 0.200 | 0.105/0.079 |
A: the first conserved region containing the endocytosis signal. B: the region containing the Kennedy-like sequences. C: the hydrophobic region D: LLP-2 domain. E: LLP-3 domain. F: LLP-3 / LLP-1 inter-region. G: LLP-1 region. ND: not determined. * Group A, B, provirus, virus alignement SE were normalized with the natural logarithm of the number of sequences. ** Results of the intra-patient study.