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. 2013 Nov 1;8(11):e79910. doi: 10.1371/journal.pone.0079910

Figure 5. The lysine 286(K286) and arginine 290(R290) residues within the first and second ZF region are critical for the nuclear localization of ZNF24.

Figure 5

(A) Diagram of the ZNF24 mutants with point mutation of the lysine(K), argine(R), serines (S), threonines (T) or lysines (K) to alanines (A) within the first and second ZF region as indicated. (B) The protein localization was analyzed similarly as in Figure 1. Patterns of localization are summarized on the left. (C) Results (mean±S.E.M., n=100) for quantitative analysis of images to determine the nuclear to cytoplasmic fluorescence ratio (Fn/c). (D) Conservation of the first and second ZF region of ZNF24 among the species.