Table 1. Secondary structure content estimated from far-UV CD spectra and predicted from sequence analysis or derived from the crystal structure [19,20].
% α-helix, % β-sheet estimation from the CD analysis | % α-helix, % β-sheet in the crystal structure | predicted % α-helix, % β-sheet | |
---|---|---|---|
CagA-N | 58, 10 | 61, 0 | - |
CagA-Ma | 29, 15 | - | 41, 9 |
CagA-Mc | 31, 11 | 39, 10 | - |
CagA-R | 6, 39 | - | 27, 7 |
a Values predicted from sequence analysis rather than the crystal structure are shown as approximately 16% of the CagA-M region was not visible in the electron density maps.