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Hematopoietic support by MDS-MSC is impaired and affected by LEN treatment. CAF-C numbers were determined after seeding 1×103 CD34+ healthy cells on MSC layers with or without LEN conditioning and co-culture for 28 days. Results are expressed as mean ± SEM of independent cases. Numbers were Healthy=6, LR-5q=6, LR=5 and HR=5. ΩIndicates difference between healthy and MDS groups without treatment. Significance was set as *P≤0.05; **/ΩΩP≤0.005; ***/ΩΩΩP≤0.001.
