Table 2. Potential risk factors of osteomyelitis of the jaw in all osteoporosis patients and oral bisphosphonate users.
Osteoporosis patients (46 cases, 6,923 patients) |
Bisphosphonate users (41 cases, 4,129 patients) |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Regression coefficient | Odds ratio | 95% confidence interval |
p | Regression coefficient | Odds ratio | 95% confidence interval |
p | ||||
Oral bisphosphonates, use vs. non-use | 1.605 | 4.98 | 1.94 | 12.75 | <0.01 | - | |||||
Age, +10 years | 0.247 | 1.28 | 1.03 | 1.60 | 0.03 | 0.269 | 1.31 | 1.03 | 1.67 | 0.03 | |
Sex, men vs. women | -0.911 | 0.40 | 0.14 | 1.14 | 0.09 | -1.493 | 0.22 | 0.05 | 0.95 | 0.04 | |
Diabetes, yes vs. no | 0.574 | 1.78 | 0.86 | 3.68 | 0.12 | -0.050 | 0.95 | 0.41 | 2.18 | 0.91 | |
Steroid, use vs. non-use | -0.209 | 0.81 | 0.36 | 1.84 | 0.62 | 0.509 | 1.66 | 0.78 | 3.56 | 0.19 | |
Chemotherapy, use vs. non-use | -0.925 | 0.40 | 0.09 | 1.66 | 0.21 | -0.890 | 0.41 | 0.10 | 1.73 | 0.22 | |
Antirheumatic drugs, use vs. non-use | -0.045 | 0.96 | 0.44 | 2.08 | 0.91 | -0.294 | 0.75 | 0.31 | 1.77 | 0.51 | |
Biologic agents, use vs. non-use | 0.756 | 2.13 | 0.57 | 7.91 | 0.26 | 1.007 | 2.74 | 0.71 | 10.60 | 0.14 | |
Sex-chemotherapy interaction | 2.460 | 11.70 | 1.46 | 93.64 | 0.02 | 3.067 | 21.48 | 2.14 | 215.21 | 0.01 |
*Risk indices were calculated by the sum of risk factors of an individual patient multiplied by the regression coefficient.