Table 2. Key Model Parameters for Simulations.
Model Parameter Definition | Value | Reference |
Prob. of transmission from one sharing event () | 0.00995 | [36] |
Rate of importing infection into a node () | varies | [36] |
Proportion of spontaneously clearing nodes | 0.25 | [59], [79] |
Prevalence at end of burn-in phase | 0.56 | [36] |
Edgewise weekly probability of sharing (both less-frequent users) | 0.19 | [36] |
Edgewise weekly probability of sharing (one less-frequent user) | 0.18 | [36] |
Edgewise weekly probability of sharing (two more-frequent users) | 0.24 | [36] |
Incidence rate ratio for imported infections of freq. vs. non-freq. users | 1.3 | [36] |
Mean time to chronic spontaneous clearance (years) | 200 | [80] |
Duration of latent period (weeks) | 2 | [81] |
Mean time to acute spontaneous clearance (weeks) | 7 | [79] |
Duration of acute phase (weeks) | 26 | by definition |
Key model parameters used for transmission and treatment simulations. Less-frequent users have injecting behaviour less than weekly (on average) while more-frequent users have injecting behaviour at least weekly (on average). Rate of importing infection [36] is modified to account for varying prevalence.