Table 2.
Antinociceptive effect of crude methanol extract of X. indicum stems (XISE) in the acetic acid-induced gastric pain model mice
| Treatment | Dose (mg/kg body weight) | Mean number of abdominal constrictions | % inhibition |
|---|---|---|---|
| Control (Group 1) |
10 ml |
4.8 ± 0.20 |
- |
| Aspirin (Group 2) |
200 mg |
3.0 ± 0.55 |
37.5* |
| (XISE) |
50 mg |
2.8 ± 0.86 |
41.7* |
| (XISE) |
100 mg |
2.4 ± 1.08 |
50.0* |
| (XISE) |
200 mg |
2.2 ± 1.16 |
54.2* |
| (XISE) | 400 mg | 2.0 ± 0.84 | 61.0* |
All administrations (aspirin and extract) were made orally. Values represented as mean ± SEM, (n = 5); *P < 0.05; significant compared to control.