Table 2. Liver/body weight ratio and results of biochemical analyses according to the duration of DEN administration in each group.
At 10 weeks of DEN administration | ||||||||||
Diet | n | Body weight (g) | Liver weight (g) | Liver/body weight (%) | ALT (U/L) | T.bilirubin (mg/dl) | Ammonia (µg/dl) | |||
3% Casein | 5 | 427±31.1 | 11±1.7 | 2.6±0.4 | 59.2±13.48 | 0.16±0.05 | 211.8±55.94 | |||
3% BCAA | 5 | 420±29.8 | 9.9±1.2 | 2.3±0.2 | 52.6±7.3 | 0.1±0.00 | 193.6±23.92 | |||
6% BCAA | 5 | 417±20.2 | 10.3±1.6 | 2.5±0.3 | 70±15.59 | 0.16±0.05 | 247.25±17.27 | |||
At 14 weeks of DEN administration | ||||||||||
Diet | n | Body weight (g) | Liver weight (g) | Liver/body weight (%) | ALT (U/L) | T.bilirubin (mg/dl) | Ammonia ( µg/dl) | |||
3% Casein | 5 | 463.9±42.3 | 22.1±5.2 | 4.8±1.1 | 126.8±70.46 | 0.42±0.18 | 448.4±68.96 | |||
3% BCAA | 5 | 464.4±39.6 | 20.1±4.9 | 4.3±0.8 | 105.6±49.45 | 0.32±0.16 | 347.2±80.01 * | |||
6% BCAA | 5 | 450±30.2 | 19.2±3.2 | 4.3±0.9 | 109.6±29.67 | 0.38±0.13 | 244±45.73 *** | |||
At 16 weeks of DEN administration | ||||||||||
Diet | n | Body weight (g) | Liver weight (g) | Liver/body weight (%) | ALT (U/L) | T.bilirubin (mg/dl) | Ammonia ( µg/dl) | |||
3% Casein | 5 | 484.7±51.6 | 27±3.8 | 5.6±1.0 | 152.2±61.73 | 1.45±0.65 | 415.8±66.27 | |||
3% BCAA | 5 | 464.6±36.3 | 25.6±2.2 | 5.5±0.8 | 117±34.63 | 0.76±0.22 * | 361±36.57 | |||
6% BCAA | 5 | 457.4±43.7 | 20.7±3.1 | 4.5±0.7 * | 134.6±23.95 | 0.6±0.37 * | 274.6±32.99 ** | |||
At 19 weeks of DEN administration | ||||||||||
Diet | n | Body weight (g) | Liver weight (g) | Liver/body weight (%) | ALT (U/L) | T.bilirubin (mg/dl) | Ammonia ( µg/dl) | |||
3% Casein | 5 | 494.9±34.1 | 25.2±3.7 | 5.1±1.0 | 122.4±37.75 | 0.24±0.05 | 368.6±56.56 | |||
3% BCAA | 5 | 515.1±26.2 | 33.1±7.7 | 6.5±1.7 | 170±32.52 | 0.25±0.06 | 349.4±28.39 | |||
6% BCAA | 5 | 504.4±51.9 | 31.1±8.7 | 6.2±1.6 | 119.2±12.66 | 0.4±0.16 | 282.8±30.7 * |
Values shown are means ± SD.
Significantly different from the 3% casein group at P<0.05.
Significantly different from the 3% casein group at P<0.005.
Significantly different from the 3% casein group at P<0.0005.