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. 2008 Dec 22;2(1):40–61. doi: 10.1111/j.1751-7915.2008.00063.x

Table 2.

The most frequent amino acid substitutions found in GyrA and ParC of non‐fermentative Gram‐negative bacilli.

Microorganism	Amino acid change				MIC (mg l⁻¹) CIP
Microorganism	GyrA		Parc		MIC (mg l⁻¹) CIP
Pseudomonas aeruginosa wt	Thr‐83	Asp‐87	Ser‐80	Glu‐84
	Ile				2
	Ile		Leu		8
	Ile			Lys	32
	Ile	Gly/Asn	Leu		128
Acinetobacter baumannii wt	Ser‐83	Asp‐87	Ser‐80	Glu‐84
	Leu				4–64
	Leu		Leu		32–128

MIC, minimum inhibitory concentration; CIP, ciprofloxacin.