1452771_s_at |
FACL3 |
Fatty acid coenzyme A ligase, long chain 3 |
1.44 |
1418911_s_at |
FACL4 |
Fatty acid‐coenzyme A ligase, long chain 4 |
1.38 |
1417434_at |
GPD2 |
Glycerol phosphate dehydrogenase 2, mitochondrial |
1.34 |
1429533_at |
IMMT |
Inner membrane protein, mitochondrial |
1.32 |
1450612_a_at |
PEMT |
Phosphatidylethanolamine N‐methyltransferase |
1.31 |
1449137_at |
PDHA1 |
Pyruvate dehydrogenase E1 alpha 1 |
1.268 |
1420044_at |
NRD1 |
Nardilysin, N‐arginine dibasic convertase, NRD convertase 1 |
1.26 |
1434996_at |
SLC25A16 |
Solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 |
1.242 |
1453886_a_at |
SLC25A26 |
Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 26 |
1.24 |
1429971_at |
TXNRD2 |
Thioredoxin reductase 2 |
1.24 |
Down‐regulated genes in PWS‐IC muscle |
AFFY ID |
Gene symbol |
Gene description |
Fold change |
1452257_at |
BDH |
3‐Hydroxybutyrate dehydrogenase (heart, mitochondrial) |
–2.55 |
1422905_s_at |
FMO2 |
Flavin containing monooxygenase 2 |
–2.04 |
1422997_s_at |
MTE1 |
Mitochondrial acyl‐CoA thioesterase 1 |
–1.66 |
1448988_at |
ACADL |
Acetyl‐coenzyme A dehydrogenase, long‐chain |
–1.56 |
1430969_at |
MTCH2 |
Mitochondrial carrier homolog 2 (C. elegans) |
–1.55 |
1416203_at |
AQP1 |
Aquaporin 1 |
–1.52 |
1450387_s_at |
AK4 |
Adenylate kinase 4 |
–1.49 |
1422493_at |
CPOX |
Coproporphyrinogen oxidase |
–1.47 |
1444394_at |
ACAD9 |
Acyl‐Coenzyme A dehydrogenase family, member 9 |
–1.42 |
1449443_at |
DECR1 |
2,4‐Dienoyl CoA reductase 1, mitochondrial |
–1.39 |
1431148_at |
AK3L |
Adenylate kinase 3 alpha‐like |
–1.34 |
Up‐regulated genes in PWS‐IC brain |
AFFY ID |
Gene symbol |
Gene description |
Fold change |
1451623_at |
MRPL15 |
Mitochondrial ribosomal protein L15 |
1.98 |
1458404_at |
NDUFB8 |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 |
1.77 |
1417823_at |
GCAT |
Glycine C‐acetyltransferase (2‐amino‐3‐ketobutyrate‐coenzyme A ligase) |
1.55 |
1419362_at |
MRPL35 |
Mitochondrial ribosomal protein L35 |
1.51 |
1421829_at |
AK4 |
Adenylate kinase 4 |
1.46 |
1457790_at |
ASB3 |
Ankyrin repeat and SOCS box‐containing protein 3 |
1.45 |
1450948_a_at |
MRPL1 |
Mitochondrial ribosomal protein L1 |
1.44 |
1421874_a_at |
MRPS23 |
Mitochondrial ribosomal protein S23 |
1.41 |
1424164_at |
MRPL50 |
Mitochondrial ribosomal protein L50 |
1.41 |
1422095_a_at |
TYKI |
Thymidylate kinase family LPS‐inducible member |
1.40 |
Down‐regulated genes in PWS‐IC brain |
AFFY ID |
Gene symbol |
Gene description |
Fold change |
1422008_a_at |
AQP3 |
Aquaporin 3 |
–2100.84 |
1417614_at |
CKM |
Creatine kinase, muscle |
–6.85 |
1431739_at |
MTO1 |
Mitochondrial translation optimization 1 homolog (S. cerevisiae) |
–1.95 |
1442331_at |
ALAS1 |
Aminolevulinic acid synthase 1 |
–1.82 |
1430969_at |
MTCH2 |
Mitochondrial carrier homolog 2 (C. Elegans) |
–1.80 |
1444489_at |
SLC25A12 |
Solute carrier family 25 (mitochondrial carrier, Aralar), member 12 |
–1.72 |
1441030_at |
RAI14 |
Retinoic acid induced 14 |
–1.50 |
1453524_at |
KIF5B |
Kinesin family member 5B |
–1.40 |
1418987_at |
PLA2G2D |
Phospholipase A2, group IID |
–1.37 |
1440579_at |
MIB1 |
Mindbomb homolog 1 (Drosophila) |
–1.31 |