Table 1.
Clinical and demographic characteristics of study population
| Parameter | N | Mean ± SD | Geometric Mean and 95% CI |
|---|---|---|---|
| Age at evaluation (years) | 71 | 16.3 ± 4.0 | |
| Male (%) | 29/71 (41%) | ||
| Height (cm) | 71 | 165 ± 14 | |
| Weight (Kg) | 71 | 66 ± 23 | |
| Body surface area (BSA; m2) | 71 | 1.71 ± 0.34 | |
| Hypertension (%) | 27/71 (38%) | ||
| Serum creatinine (mg/dl) | 70 | 0.74 ± 0.22 | 0.71 (0.66–0.76) |
| Ang-1 (ng/ml) | 71 | 35.52 ± 21.03 | 27.57 (22.56 – 33.69) |
| Ang-2 (pg/ml) | 71 | 2.35 ± 0.96 | 2.16 (1.96 – 2.39) |
| VEGF (pg/ml) | 70 | 2997 ± 5327 | 107.2 (42.78 – 268.6) |
| Urinary creatinine (mg/24h) | 68 | 1365.35 ± 609.50 | 1250.24 (1129.1 – 1384.4) |
| Urinary protein (g/24h) | 67 | 0.20 ± 0.28 | 0.14 (0.12 – 0.17) |
| Creatinine clearance (ml/min/1.73m2) | 70 | 130.24 ± 29.40 | 125.02 (118.85 - 139.73) |
| Total renal volume (mm3) | 61 | 653,795 ± 573,871 | 506,345 (423,634 – 604,464) |
| Total cyst volume (mm3) | 61 | 430,273 ± 534,914 | 254,174 (194,691 – 331,832) |
| Renal cyst count | 61 | 74.5 ± 42.6 | |
| LVMI (g/m2) | 66 | 61.81 ± 22.20 | 58.13 (53.29 – 63.41) |
Abbreviations: Ang, angiopoietin; BSA, body surface area; CI, confidence interval; LVMI, left ventricular mass index; VEGF, vascular endothelial cell growth factor.