Table 4.

Multivariate Regression Analysis of IMT Change and CAC Progression.

A. IMTa Progression, Internal carotid
Risk Factor	Beta-coefficient (μm) (SE)	p-value
Intercept	-0.24 ± 0.1	0.05
Age	0.008 ± 0.003	0.002
Baseline high triglycerides (≥150mg/dL)	0.14 ± 0.04	<0.001
Pack-years tobacco	0.003 ± 0.001	0.03
B. IMTa Progression, Common carotid
Risk Factor	Beta-coefficient (μm) ± SE	p-value
Intercept	-0.03 ± 0.03	0.35
Cholesterol (mg/dL)	0.0002 ± 0.0001	0.005
Age	0.002 ± 0.0006	<0.001
Nadir CD4+ (100 cells/mm3)	0.005 ± 0.002	0.03
PIb use at baseline	0.02 ± 0.008	0.05
C. CACc progression
Risk Factor	Odds Ratio (Confidence Interval)	p-value
Baseline diabetes	7.4 (2.5,21.5)	<0.001
HIV viral load (log 10 copies/mL)	1.7 (1.2,2.4)	0.001
HAARTd duration (months)	1.02 (1.01,1.03)	0.004

^aIMT, carotid intima-media thickness

^bPI, protease inhibitor

^cCAC, coronary artery calcium

^dHAART, highly active antiretroviral therapy.