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. 2013 May 15;43(8):2043–2054. doi: 10.1002/eji.201243296

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© 2013 The Authors. European Journal of Immunology published by Wiley-VCH Verlag GmbH & Co. KGaA Weinheim.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Immunophenotyping of freshly isolated population III CD161+ Treg cells. (A) The percentages of Treg cells staining positive for CD39 (left) and HLA-DR (right) in population III CD161⁻ and CD161⁺ Treg cells is shown. Paired data from five independent experiments are shown. (B–G) Gene expression profiling of freshly isolated population I CD161⁻, population III CD161⁻, and population III CD161⁺ Treg cells for (B) FOXP3, (C) RORC, (D) FOXP3/RORC ratio, (E) CTLA-4, (F) ICOS, and (G) Helios is shown. Individual data from three independent healthy donors are shown.